Kratom has been used in Southeast Asia.
15 total deaths in the US related to Kratom. However, there's only 1 case where Kratom was the only substance found in their system. 44 deaths world wide.
Tropical evergreen tree in rubicae family. Generally, the leaves are dried, ground and eaten. Brewing a tea seems to be the most effective method. Extracts seem to be lacking some of the effects On a smaller scale, fresh leaves are also
No side effects found in mice. MCCURDY found 0 deaths in mice given large amounts of kratom. Toxicity does not appear to be an issue.
Opiate deaths are caused by respiratory arrest.
Mu Opioid Receptor activity is independent of the protein Beta Arrestin. These pathways that become active are related to the side effects of opiates/opioids.
OTHER COMMON ALKALOIDS
Effects stress response. Cortisol.
Opiate Addiction Treatment
Seizure, Liver and Kidney Failure.
CIT OF SAN DIEGO