Tuesday, May 4, 2021
Sunday, March 21, 2021
Monday, March 15, 2021
EDIT: Has arrived in SFO and cleared customs. Will be enroute shortly and eta is Friday 3/17
Plane has left Singapore and is in route to SF0 as we speak. It will probably be another day to get through customs, then should be here by the 18th or 19th.
This was ordered 2 months ago, and is finally here. This is the Supergreen MD supplier, which is a strain that I've carried since 2017.
UPDATE: Approval for high risk merchant account is currently pending. The main reason we have been married to this site is because every processor uses a different gateway, which requires us to frequently change the website. After about a dozen sites, you start to lose motivation.
We will have a new permanent site with official payment processor.
Thursday, March 11, 2021
As a Vendor of something potentially addictive, I constantly have this inner dialogue / debate about whether I am adequately informing people about the dangers of Kratom. I'm perpetually paranoid about getting people addicted because they were ignorant or misinformed. Let's take a look at the potential costs and the potential benefits, so that we can all do our own analysis before making such an important decision. As long as we are making a well informed decision, I am confident that we will make the correct one.
Understanding the plant is necessary in order to maximize the utility of this plant and avoid some of the pitfalls of addiction/abuse. This is partly why I'm so obsessed with uncovering the science that sometimes gets buried in the hype. There is undoubtedly a ton of misinformation in this industry, along with America in general. It appears to be a current trend for whatever reason. It's obviously incumbent on the individual to decide whether something is believable or not. In my mind, only the principles that can't be backed by evidence or theory should be shared. Anecdotal accounts can't really show more than a possible correlation between variables. But, sometimes that's good enough. it depends on the context.
There is an entire subreddit of angry people who say that Kratom ruined their lives and is 20K members deep. The subreddit r/kratom is 100k members. A recent survey showed that 20% of users in the US are addicted, vs 10% indigenously. A distinction should be made between addiction and physical dependency. Dependence is use to a point where it becomes necessary to use to avoid withdrawal or rebound. Addiction is use despite negative consequences, psychological and/or physical.
How negative do they have to be to count?
I personally think that if you're stressed about your use, that's enough. Even if you're only slightly stressed, I feel like that is addiction. If, on the other hand, you are not concerned with the fact that you cannot control your use, then I feel like it won't be an issue, unless of course there is some other negative consequence that outweighs the potential (physiological) benefit. So, only when costs outweigh the benefits, will there be negative consequences from it's use as a med: a net effect Just the fact that you are not in full control of your use is not enough to be considered addiction by my definition. This is not the prevailing definition of addiction in the recovery community, however. Dependence of any kind to any substance (not considered medicine) is considered addiction by the self help community (somehow not cigarettes or caffeine though), but not without dissonance. Replacement therapy like with suboxone is considered ok, but for some reason, in many circles, Kratom use is not. The main issue is that the FDA has not approved kratom for anything, not even as a dietary supplement. The entire medical community revolves around the FDA, unfortunately, who is excessively anti-kratom. They are so anti that they have been caught spreading propaganda falsehoods on numerous occasions, diminishing their credibility as a public health agency. So much of the politics has to do with the misunderstandings and the stigmas associated with an incredibly medicinal plant. Just the idea that there are scientists on the other side that want this banned makes me quiver.
Because of the potency and possible addictive nature of the compound 7ohm, one must use cost benefit analysis when determining whether to use it. Unfortunately, all Opioid medications are going to have tradeoffs. The FDA approves medications that kill people for a reason. This is because the diseases that they treat most certainly will, or have worse consequences. The use of cost benefit analysis is the cornerstone of modern western medicine. Some people will say that the negative side is not negative enough for addiction to be considered a legitimate concern with this as a medication. The main reasons are the clear cut ceiling effect and the lack of beta arrestin.
Although 7ohm is a G Protein signaled pathway to the MOR, there is addiction potential, tolerance, and respiratory depression at the level a fraction of opiates. Regardless, it needs to be respected as a powerful opioid. Responsible use, whether recreational or medicinal is what will ensure that the plant remains legal. There is a woman arguing that kratom withdrawal is what made here son commit suicide, although there is little evidence. Arguably, there could be deficit of neurotransmitters during rebound, causing instability. It would be hard to tell if that is ultimately what caused it. Being well informed on what it does and how to use it is essential, I feel. So, let's identify what they are, and calculate the probability they will occur. This way we can all make an informed decision on how to use this substance.
Although it has been used for hundreds of years by indigenous people, it has not been studied extensively by science until just recently. So, while there is historical basis, there is not that much in the way of scholarly studies. These are historically based, or documented by science.
Addiction (Compuslive Redosing)
Dependence / Withdrawal Syndrome
Hepatic Face (Dark Spots, Not reported by Americans)
Hair Loss/Thinning (Not reported by Asian users)
GI Irritation (Acidity)
Addiction Treatment (New evidence shows efficacy with cigarette cessation, and alcoholism.)
Antidepressant effects (Serotonin)
Reduced Stress Response (Reduced Cortisol in Rats)
Antipsychotic (Showed Improvement in Dissociation, Alzheimer's potential?)
Analgesia Muscle Relaxer
Hypothalamus Regulator (Appetite Suppressor)
Lower Blood Pressure (Raise or Lower)
Lower Blood Sugar (A1C)
Diarrhetic (Cost or Benefit)
High Cholesterol (Not much evidence exists for kratom per se, but anecdotally as opiates in general have a tendency to do this, there is a recent study of 100 kratom users who showed lower cholesterol)
Please add to the list as you see fit when doing your own analysis.
Keep in mind, that heart disease is the number one cause of death (650k) in this country, 1 in 10 people have diabetes, there were 70k opioid overdose deaths last year, 95k alcohol related deaths. 10% of worldwide disability claims are from depression. That's a lot of benefit to weigh against costs. I imagine the cost benefit curve is going to be a little different depending on the reason you're using Kratom.
I would argue that medicinally speaking, overall, the benefits far outweigh the costs. However, it will be different for every individual as the potential cost of addiction will be different based on your personality, along with the potential benefit of why you use it. Only you can calculate what the probability and cost of your getting addicted to anything is.
Used responsibly, this plant has very little downside, as far as the evidence suggests. It has a built-in, self-regulating function that makes it harder to abuse than a typical psychoactive compound. The danger of compulsive redosing is somewhat diminished because of wobbles. You can only take so much before it shuts down on you. Evidence shows that higher doses (irresponsible use if you will) actually prevent addiction, tolerance, and withdrawal to 7ohm.
Up until recently, how Kratom works has been a bit of a mystery. However, now, the cost benefit is clear. Kratom is the cure to our global opioid crisis and then some. It could mean a healthier future for the world if used correctly and responsibly. Hopefully, we will go down as the generation who paved the way for this to become ubiquitous in American Culture.
Be informed. Spread the Word. The future is Kratom. Did this just turn into a pharmaceutical commercial? Your chance to live longer? One could almost argue that you're better off, health wise, being a kratom user (if you're savvy enough to know about it).
Friday, February 26, 2021
Friday, January 8, 2021
The domain: 7ohm.com doesn't seem to be working for some reason. None of the links show up. It works fine on all of my devices, but others have reported dead links when using 7ohm.com instead of 7ohm.info. I'm not sure what could explain it.
So, if you came here using 7ohm.com, you have to use 7ohm.info, or https://www.7ohm.info/p/seven-ohm-botanicals-botanical-specimen.html.
I don't know what the cause is, and I have no idea how to solve it. It doesn't make any sense to me. It's technically a domain forwarding process. There's no plausible reason why the links would be missing when it's going to the same site. It's the weirdest thing.
Thursday, January 7, 2021
Most Potentiates that people use for Kratom are cyp3a4 inhibitors. The rationale behind this is that since this enzyme metabolizes 65% of known drugs, a lack of it would cause the alkaloids to build in the bloodstream causing a pronounced effect that lasts longer. This dangerous drug interaction with an inhibitor like grapefruit juice is what you are warned about on many prescription drug bottles.
Recent research has been groundbreaking. We've discovered that the opioid (7ohm) on par with Morphine found in kratom is a metabolite and only found in trace amounts in the leaf. This alkaloid is converted primarily by the same enzyme mentioned above. So, while we were trying to get a greater opioid effect by inhibiting said enzyme, we may have actually been reducing the opioid effect. This would theoretically mean that the effects would be primarily from the alkaloid Mitragynine. Mitragynine is the reason we have stimulation through adenosine receptor antagonism, much like Caffeine.
So, theroretically, you would get more stim from an inhibitor, and more opioid from an inducer. Try this experiment: take the same amount of the same strain of kratom for a week (or a day) while taking an inhibitor, then try it for a week (or whatever) with an inducer. See if you get different effects. Also theoretical: wobbles should be cured by taking an inducer assuming you believe that wobbles are caused by the "great neuromuscular blockade" effect of Mitagrynine (as cited by one study.
[b]Inducers (increase cyp3a4)
]St. John’s wort [14, 15, 16]
Capsaicin [17, 18]
Common valerian 
Echinacea purpurea 
Vitamin D and UV exposure 
Being female 
Fatty acids 
Polycyclic aromatic hydrocarbons (PAH) found in cigarettes 
Aflatoxin B1 
Some drugs such as carbamazepine  and dexamethasone 
[b]Inhibitors (decrease cyp):
Grapefruit juice (and its compounds bergamottin, naringenin, and paradicin-A) [26, 4, 27]
Starfruit juice 
Aloe vera juice 
Mixed vegetable juices 
Garden cress [32, 33]
Green tea [4, 35]
Black pepper [36, 37]
Raspberry leaf 
Milk thistle (compounds silybin and isosilybin) 
Good link explaining the enzyme and citing studies: ]https://www.medsafe.govt.nz/profs/PUArticles/March2014DrugMetabolismCytochromeP4503A4.htm#:~:text=The%20liver%20and%20small%20intestine%20have%20the%20highest%20CYP3A4%20activity.&text=Potent%20inhibitors%20of%20CYP3A4%20include,John's%20Wort%20and%20glucocorticoids
I know people don't like talking much about this possible side effect.The topic may even have been banned at one point on r/kratom. It's possible that addressing it might help ease this paranoia during a time when we're all scarfing down considerable amounts of green sludge. Or, if you weren't paranoid about it before this, you might be after reading this. One of the most fucked up side effects from Kratom that people have discussed is about alopecia (hair loss). Although people have called bullshit on it, people have also posted pictures and documented their ordeal mainly on r/quittingkratom. The good thing is that it seems to grow back once you quit. Nobody can figure out what's going on exactly and what's causing it, but luckily it does seem to grow back once you quit. It just sucks that you have to quit, right? In looking at a bunch of lab tests recently, I noticed an alarming trend among red kratom (not red vein): mold.
All Red Kratom is essentially bentuangie and virtually all strains have some of it mixed in. They allegedly try to ferment the leaf by putting it in plastic bags and then in then sun until it turns red. Why they do this seems to be nothing more than trying to get a red color. We'll never know because here's a serious disconnect between effect and muslim Indonesian. Please don't say anything about red "vein" kratom because it doesn't exist. Let me clarify: it does exist, but every plant produces it at one point in their life, and there is no scientific evidence that it has a different alkaloid profile.
Even if there were a different alkaloid profile to be found in different vein color, Indonesian farmers are not differentiating between vein colors when harvesting so it's moot to even consider it as factor. Additionally, recent research says that most of the psychoactive effects are caused by mitragynine, and the other alkaloids (with the exception of mitraphyline) are found in too small of amounts to make a significant impact on effect. Mitraphyiine is a strong anti-inflammatory that has shown promise in treating cancer. All "strains" from Indonesia are blends of red and green kratom.
There seems to be an inherent flaw in the way red kratom is made, and this causes it to grow mold. Fermentation isn't really feasible when it comes to kratom as there are no precursors present (sugar, yeast, etc) in a plastic bag filled with leaves and put in the sun. I'm not sure why it is that we think fermentation occurs in this kind of environment. With failed fermentation most likely comes mold growth. How do I know this? I looked at a bunch of lab tests of a bunch of different types of kratom from the same farmer and found that bentuangie is very susceptible to mold. Since it's blended into virtually every strain this could cause problems. Most of the red strains that have this blended in also failed the mold test. Bali, Borneo, etc... I wouldn't be as concerned with toxicity, as I would be with an allergic reaction, especially if you're also asthmatic. Coincidentally, mold allergies can cause hair loss. So, now you have 2 reasons to avoid Bentuangie, especially if it hasn't been lab tested for microbes. For all of those that feel that reds are void of effect, it may be because this drying process severely degrades Mitragynine (some of the levels of Mg were as low as .3%). My assumption is that the longer you leave it in the bag/sun, the more of it is degraded. What we learned from this is that there does appear to be value in reduced levels of Mitragynine. This reduced level of MG could be the reason that reds are perceived to have a more opioid effect.
To validate our theory we just need to find out if hair loss sufferers were allergic to mold along with which strain and how much they were taking.
Symptoms of Mold Allergy
Runny or stuffy nose
Cough and postnasal drip
Itchy eyes, nose and throat
Dry, scaly skin
Finally, there is something that needs to be said about moderate levels of Mitragynine, which is the most common in consistently popular strains. the average was around 1.5%. Reds averaged .9. Sun dried greens (Supergreen) were 1.4%. High levels of Mitragynine seem to be void of opioid effect possibly because of the inhibition of the cyp3a4 enzyme in our bodies, preventing conversion of 7ohm. But, more on that in another post.
Wednesday, December 30, 2020
The practice of tainting Kratom has not been very successful thus far in history. The only two times that I've been able to find where it's happened, people have died. I'm sure we agree that it's a pretty stupid thing to do. Killing off your customers doesn't make much economic sense. That's why adulterating Kratom doesn't happen, much like how weed never got "laced" anonymously. Let's look at the statement "because a company is financially motivated, they would adulterate Kratom without issue". Here is why nobody's doing that from an economic standpoint:
1) Cost benefit Analysis Failure: You'd have to make a significant amount of money by selling adulterated Kratom to offset the potential liability that killing someone could be. Potential cost is way higher including fiscal suicide from a lawsuit. Potential benefit is marginal at best, as there is only so much Kratom will fetch.
2) A large market already exists for Kratom in it's natural form. By adulterating your product, you are essentially changing it, which has an entirely different demand curve. There's demand for such a product for sure, but it's not the same market as Kratom. You would essentially be giving the consumer something they don't want through deception. The consumer is most likely going to be pissed when they inevitably figure it out. You'd be better off marketing directly to those who actually want it: those who prefer an extra oomph maybe.
3) You're giving something away for nothing. Free adulterant. There are people who will pay for it. Why not just advertise that your Kratom is "enhanced" and charge more? If a company were rumored to "spike" their Kratom, I bet people would line up. There is a different market for this type of consumer.
You might argue that Companies kill people for profit all the time. Yeah, they do it when the potential benefit outweighs the potential cost. When a Car company decides whether to recall a car or not, they look at what the cost of the recall would be and compare it to what the cost of the lawsuits from lost life will be. The benefit of savings from the cost of recall have to outweigh the potential cost of life in order for the recall to happen. Does it get more unethical than that? They're willing to let people die over money. But it makes economic sense. Cost benefit analysis is a fundamental principle of economics, as is maximizing profit at all cost.
The case of adulterating Kratom has nothing to do with ethics or morality. It's simple economics. A profit motivated company would almost certainly prefer to give their customer what they demand. Cost benefit analysis says a profit seeking person/company would not engage in such deceptive practices. It's the same reason why nobody's "Lacing" your weed. Stop being paranoid (At least you were high when you thought that about weed). Even the AKA released a follow up to their unfounded "Adulterated Kratom Warning". What's stopping people from messing with your Kratom? There is no law to stop them from doing it except the law of economics (Cheezy, I know, Couldn't help self). Who would take on a money losing business venture? Nobody is going to choose to lose money, are they? The probability of success from adulterating Kratom is low, plain and simple. You might be some scumbag willing to do anything for money, but I guarantee you're not going to take on a scam with such a high potential cost, low possible payout, and high probability for failure.
You might as well rob a bank (Do they even do that anymore?) I can't seem to come up with a profile for what a kratom spiking individual would be like. Anyone? Fetishism? Psych disorder? Just a strong urge to anonymously give away drugs?
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